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Cooperation of Mtmr8 with PI3K Regulates Actin Filament Modeling and Muscle Development in Zebrafish

BACKGROUND: It has been shown that mutations in at least four myotubularin family genes (MTM1, MTMR1, 2 and 13) are causative for human neuromuscular disorders. However, the pathway and regulative mechanism remain unknown. METHODOLOGY/PRINCIPAL FINDINGS: Here, we reported a new role for Mtmr8 in neu...

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Detalhes bibliográficos
Main Authors: Mei, Jie, Li, Zhi, Gui, Jian-Fang
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2656612/
https://ncbi.nlm.nih.gov/pubmed/19325702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004979
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