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Trichostatin A treatment of cloned mouse embryos improves constitutive heterochromatin remodeling as well as developmental potential to term

BACKGROUND: Genome reprogramming in early mouse embryos is associated with nuclear reorganization and particular features such as the peculiar distribution of centromeric and pericentric heterochromatin during the first developmental stage. This zygote-specific heterochromatin organization could be...

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Detalhes bibliográficos
Main Authors: Maalouf, Walid E, Liu, Zichuan, Brochard, Vincent, Renard, Jean-Paul, Debey, Pascale, Beaujean, Nathalie, Zink, Daniele
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2656487/
https://ncbi.nlm.nih.gov/pubmed/19210795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-213X-9-11
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