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Alterations in Glucocorticoid Negative Feedback Following Maternal Pb, Prenatal Stress and the Combination: a Potential Biological Unifying Mechanism for their Corresponding Disease Profiles

Combined exposures to maternal lead (Pb) and prenatal stress (PS) can act synergistically to enhance behavioral and neurochemical toxicity in offspring. Maternal Pb itself causes permanent dysfunction of the body’s major stress system, the hypothalamic pituitary adrenal (HPA) axis. The current study...

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Hlavní autoři: Rossi-George, A., Virgolini, M. B., Weston, D., Cory-Slechta, D.A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2656375/
https://ncbi.nlm.nih.gov/pubmed/18977374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2008.10.003
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