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Regulatory T cells in systemic lupus erythematosus: past, present and future

Regulatory/suppressor T cells (Tregs) maintain immunologic homeo-stasis and prevent autoimmunity. In this article, past studies and recent studies of Tregs in mouse models for lupus and of human systemic lupus erythematosus are reviewed concentrating on CD4(+)CD25(+)Foxp3(+ )Tregs. These cells consi...

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Détails bibliographiques
Auteur principal: Horwitz, David A
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2656253/
https://ncbi.nlm.nih.gov/pubmed/19040771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2511
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