Loss of Tsc2 in radial glia models the brain pathology of tuberous sclerosis complex in the mouse

Tuberous sclerosis complex (TSC) is an autosomal dominant, tumor predisposition disorder characterized by significant neurodevelopmental brain lesions, such as tubers and subependymal nodules. The neuropathology of TSC is often associated with seizures and intellectual disability. To learn about the...

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Главные авторы: Way, Sharon W., McKenna, James, Mietzsch, Ulrike, Reith, R. Michelle, Wu, Henry Cheng-ju, Gambello, Michael J.
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2009
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2655769/
https://ncbi.nlm.nih.gov/pubmed/19150975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddp025
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