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A rapid simple approach to quantify chromosome conformation capture

Chromosome conformation capture (3C) is a powerful tool to study DNA looping. The procedure generates chimeric DNA templates after ligation of restriction enzyme fragments juxtaposed in vivo by looping. These unique ligation products (ULPs) are typically quantified by gel-based methods, which are pr...

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Autori principali: Abou El Hassan, M., Bremner, R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2655679/
https://ncbi.nlm.nih.gov/pubmed/19181703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp028
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