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A rapid simple approach to quantify chromosome conformation capture

Chromosome conformation capture (3C) is a powerful tool to study DNA looping. The procedure generates chimeric DNA templates after ligation of restriction enzyme fragments juxtaposed in vivo by looping. These unique ligation products (ULPs) are typically quantified by gel-based methods, which are pr...

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Detalhes bibliográficos
Main Authors: Abou El Hassan, M., Bremner, R.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2655679/
https://ncbi.nlm.nih.gov/pubmed/19181703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp028
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