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Diene-modified nucleotides for the Diels–Alder-mediated functional tagging of DNA
We explore the potential of the Diels–Alder cycloaddition for the functional tagging of DNA strands. A deoxyuridine triphosphate derivative carrying a diene at position 5 of the pyrimidine base was synthesized using a two-step procedure. The derivative was efficiently accepted as substrate in enzyma...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2655660/ https://ncbi.nlm.nih.gov/pubmed/19139071 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn1066 |
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