New Genomic Structure for Prostate Cancer Specific Gene PCA3 within BMCC1: Implications for Prostate Cancer Detection and Progression

BACKGROUND: The prostate cancer antigen 3 (PCA3/DD3) gene is a highly specific biomarker upregulated in prostate cancer (PCa). In order to understand the importance of PCA3 in PCa we investigated the organization and evolution of the PCA3 gene locus. METHODS/PRINCIPAL FINDINGS: We have employed cDNA...

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Detalhes bibliográficos
Main Authors: Clarke, Raymond A., Zhao, Zhongming, Guo, An-Yuan, Roper, Kathrein, Teng, Linda, Fang, Zhi-Ming, Samaratunga, Hema, Lavin, Martin F., Gardiner, Robert A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2655648/
https://ncbi.nlm.nih.gov/pubmed/19319183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004995
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