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Overexpression of MazF(Sa) in Staphylococcus aureus Induces Bacteriostasis by Selectively Targeting mRNAs for Cleavage

The role of chromosomally encoded toxin-antitoxin (TA) loci in bacterial physiology has been under debate, with the toxin proposed as either an inducer of bacteriostasis or a mediator of programmed cell death (PCD). We report here that ectopic expression of MazF(Sa), a toxin of the TA module from St...

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Detalhes bibliográficos
Main Authors: Fu, Zhibiao, Tamber, Sandeep, Memmi, Guido, Donegan, Niles P., Cheung, Ambrose L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2655526/
https://ncbi.nlm.nih.gov/pubmed/19168622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00907-08
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