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Kinetics of Rab27a-dependent actions on vesicle docking and priming in pancreatic β-cells
The small GTPase Rab27a, along with the isoforms of Rab3, is present on insulin secretory granules and has been implicated in regulation of Ca(2+)-triggered exocytosis. We have used membrane capacitance measurements to define the role of Rab27a in regulating the size and refilling of distinct pools...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Blackwell Science Inc
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2655366/ https://ncbi.nlm.nih.gov/pubmed/18801842 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2008.158477 |
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