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Role of the C-Terminal SH3 Domain and N-Terminal Tyrosine Phosphorylation in Regulation of Tim and Related Dbl-Family Proteins

Dbl-related oncoproteins are guanine nucleotide exchange factors (GEFs) specific for Rho-family GTPases and typically possess tandem Dbl (DH) and pleckstrin homology (PH) domains that act in concert to catalyze exchange. Although the exchange potential of many Dbl-family proteins is constitutively a...

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Bibliografische gegevens
Hoofdauteurs: Yohe, Marielle E., Rossman, Kent, Sondek, John
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2008
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2655348/
https://ncbi.nlm.nih.gov/pubmed/18537266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi702543p
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