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Modulation of GABA(A) receptor desensitization uncouples sleep onset and maintenance in Drosophila

Many lines of evidence indicate that GABA and GABA(A) receptors make important contributions to human sleep regulation. Pharmacological manipulation of these receptors has differential effects on sleep onset and sleep maintenance insomnia. Here we show that sleep is regulated by GABA in Drosophila a...

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Bibliografski detalji
Glavni autori: Agosto, Jose, Choi, James C, Parisky, Katherine M, Stilwell, Geoffrey, Rosbash, Michael, Griffith, Leslie C
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2655319/
https://ncbi.nlm.nih.gov/pubmed/18223647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn2046
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