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Domain duplication, divergence, and loss events in vertebrate Msx paralogs reveal phylogenomically informed disease markers
BACKGROUND: Msx originated early in animal evolution and is implicated in human genetic disorders. To reconstruct the functional evolution of Msx and inform the study of human mutations, we analyzed the phylogeny and synteny of 46 metazoan Msx proteins and tracked the duplication, diversification an...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2009
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2655272/ https://ncbi.nlm.nih.gov/pubmed/19154605 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-9-18 |
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