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Comparison of methods for estimating the nucleotide substitution matrix

BACKGROUND: The nucleotide substitution rate matrix is a key parameter of molecular evolution. Several methods for inferring this parameter have been proposed, with different mathematical bases. These methods include counting sequence differences and taking the log of the resulting probability matri...

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Main Authors: Oscamou, Maribeth, McDonald, Daniel, Yap, Von Bing, Huttley, Gavin A, Lladser, Manuel E, Knight, Rob
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2655096/
https://ncbi.nlm.nih.gov/pubmed/19046431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-9-511
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