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Protein Homeostasis and Aging: Taking Care of Proteins From the Cradle to the Grave

All cells count on precise mechanisms that regulate protein homeostasis to maintain a stable and functional proteome. Alterations in these fine-tuned mechanisms underlie the pathogenesis of severe human diseases including, among others, common neurodegenerative disorders such as Alzheimer's or...

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Detalhes bibliográficos
Main Authors: Morimoto, Richard I., Cuervo, Ana M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2655025/
https://ncbi.nlm.nih.gov/pubmed/19228787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/gln071
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