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Heterochromatic Genome Stability Requires Regulators of Histone H3 K9 Methylation

Heterochromatin contains many repetitive DNA elements and few protein-encoding genes, yet it is essential for chromosome organization and inheritance. Here, we show that Drosophila that lack the Su(var)3-9 H3K9 methyltransferase display significantly elevated frequencies of spontaneous DNA damage in...

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Autors principals: Peng, Jamy C., Karpen, Gary H.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2654965/
https://ncbi.nlm.nih.gov/pubmed/19325889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000435
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