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A Toxin–Antitoxin System Promotes the Maintenance of an Integrative Conjugative Element

SXT is an integrative and conjugative element (ICE) that confers resistance to multiple antibiotics upon many clinical isolates of Vibrio cholerae. In most cells, this ∼100 Kb element is integrated into the host genome in a site-specific fashion; however, SXT can excise to form an extrachromosomal c...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Wozniak, Rachel A. F., Waldor, Matthew K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2654960/
https://ncbi.nlm.nih.gov/pubmed/19325886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000439
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