Retinoid and thiazolidinedione therapies in melanoma: an analysis of differential response based on nuclear hormone receptor expression

BACKGROUND: Metastatic melanoma has a high mortality rate and suboptimal therapeutic options. Molecular targeting may be beneficial using the rexinoid LGD1069, a retinoid × receptor selective agonist, and thiazolidinediones (TZD), PPARγ selective ligands, as novel treatments. RESULTS: Mouse xenograf...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Klopper, Joshua P, Sharma, Vibha, Berenz, Andrew, Hays, William R, Loi, Michele, Pugazhenthi, Umarani, Said, Sherif, Haugen, Bryan R
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2009
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2654861/
https://ncbi.nlm.nih.gov/pubmed/19267912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-8-16
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares