Functional Analysis of the Leading Malaria Vaccine Candidate AMA-1 Reveals an Essential Role for the Cytoplasmic Domain in the Invasion Process

A key process in the lifecycle of the malaria parasite Plasmodium falciparum is the fast invasion of human erythrocytes. Entry into the host cell requires the apical membrane antigen 1 (AMA-1), a type I transmembrane protein located in the micronemes of the merozoite. Although AMA-1 is evolving into...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Treeck, Moritz, Zacherl, Sonja, Herrmann, Susann, Cabrera, Ana, Kono, Maya, Struck, Nicole S., Engelberg, Klemens, Haase, Silvia, Frischknecht, Friedrich, Miura, Kota, Spielmann, Tobias, Gilberger, Tim W.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2009
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2654807/
https://ncbi.nlm.nih.gov/pubmed/19283086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000322
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