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Intrameal Hepatic Portal and Intraperitoneal Infusions of Glucagon-Like Peptide-1 Reduce Spontaneous Meal Size in the Rat via Different Mechanisms

Peripheral administration of glucagon-like peptide (GLP)-1 reduces food intake in animals and humans, but the sites and mechanism of this effect and its physiological significance are not yet clear. To investigate these issues, we prepared rats with chronic catheters and infused GLP-1 (0.2 ml/min; 2...

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Bibliografske podrobnosti
Main Authors: Rüttimann, Elisabeth B., Arnold, Myrtha, Hillebrand, Jacquelien J., Geary, Nori, Langhans, Wolfgang
Format: Artigo
Jezik:Inglês
Izdano: The Endocrine Society 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2654737/
https://ncbi.nlm.nih.gov/pubmed/18948395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2008-1221
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