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General Approach to the Total Synthesis of 9-Methoxy Substituted Indole Alkaloids: Synthesis of Mitragynine, as well as 9-Methoxygeissoschizol and 9-Methoxy-N(b)-methylgeissoschizol

[Image: see text] Herein the full details of the synthesis of the 9-methoxy-substituted Corynanthe indole alkaloids mitragynine (1), 9-methoxygeissoschizol (3) and 9-methoxy-N(b)-methylgeissoschizol (4) are described. Initially an efficient synthetic route to the optically active 4-methoxytryptophan...

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Detalhes bibliográficos
Main Authors: Ma, Jun, Yin, Wenyuan, Zhou, Hao, Liao, Xuebin, Cook, James M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2654583/
https://ncbi.nlm.nih.gov/pubmed/19046119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo801839t
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