Better estimation of protein-DNA interaction parameters improve prediction of functional sites

BACKGROUND: Characterizing transcription factor binding motifs is a common bioinformatics task. For transcription factors with variable binding sites, we need to get many suboptimal binding sites in our training dataset to get accurate estimates of free energy penalties for deviating from the consen...

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Auteurs principaux: Nagaraj, Vijayalakshmi H, O'Flanagan, Ruadhan A, Sengupta, Anirvan M
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2008
Sujets:
Methodology Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2654563/
https://ncbi.nlm.nih.gov/pubmed/19105805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-8-94
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