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Glutathione-S-transferases in lung and sputum specimens, effects of smoking and COPD severity

BACKGROUND: Oxidative stress plays a potential role in the pathogenesis and progression of chronic obstructive pulmonary disease (COPD). Glutathione S-transferases (GSTs) detoxify toxic compounds in tobacco smoke via glutathione-dependent mechanisms. Little is known about the regulation and expressi...

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Detalhes bibliográficos
Main Authors: Harju, Terttu, Mazur, Witold, Merikallio, Heta, Soini, Ylermi, Kinnula, Vuokko L
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2654438/
https://ncbi.nlm.nih.gov/pubmed/19077292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-9-80
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