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Transcriptional activation by TLX1/HOX11 involves Gro/TLE corepressors

The role of Groucho/transducin-like Enhancer of split (Gro/TLE) family members as corepressors of transcription is well documented. TLX1 is a homeodomain transcription factor involved in splenogenesis and neuron formation, and its aberrant expression gives rise to T-cell acute lymphoblastic leukemia...

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Autori principali: Riz, Irene, Lee, Hyo Jung, Baxter, Kristin K., Behnam, Reza, Hawley, Teresa S., Hawley, Robert G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2654413/
https://ncbi.nlm.nih.gov/pubmed/19250647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2009.01.099
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