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Lmx1a is required for segregation of sensory epithelia and normal ear histogenesis and morphogenesis

At E8.5, the LIM-homeodomain factor Lmx1a is expressed throughout the otic placode but becomes developmentally restricted to non-sensory epithelia of the ear (endolymphatic duct, ductus reuniens, cochlea lateral wall). We confirm here that the ears of newborn dreher (Lmx1a(dr)) mutants are dysmorphi...

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Détails bibliographiques
Auteurs principaux: Nichols, David H., Pauley, Sarah, Jahan, Israt, Beisel, Kirk W., Millen, Kathleen J., Fritzsch, Bernd
Format: Artigo
Langue:Inglês
Publié: 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2654344/
https://ncbi.nlm.nih.gov/pubmed/18985389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00441-008-0709-2
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