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Quality-Controlled Small-Scale Production of a Well-Defined Bacteriophage Cocktail for Use in Human Clinical Trials

We describe the small-scale, laboratory-based, production and quality control of a cocktail, consisting of exclusively lytic bacteriophages, designed for the treatment of Pseudomonas aeruginosa and Staphylococcus aureus infections in burn wound patients. Based on succesive selection rounds three bac...

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Detalhes bibliográficos
Main Authors: Merabishvili, Maya, Pirnay, Jean-Paul, Verbeken, Gilbert, Chanishvili, Nina, Tediashvili, Marina, Lashkhi, Nino, Glonti, Thea, Krylov, Victor, Mast, Jan, Van Parys, Luc, Lavigne, Rob, Volckaert, Guido, Mattheus, Wesley, Verween, Gunther, De Corte, Peter, Rose, Thomas, Jennes, Serge, Zizi, Martin, De Vos, Daniel, Vaneechoutte, Mario
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2654153/
https://ncbi.nlm.nih.gov/pubmed/19300511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004944
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