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Epitope Characterization and Variable Region Sequence of F1-40, a High-Affinity Monoclonal Antibody to Botulinum Neurotoxin Type A (Hall Strain)

BACKGROUND: Botulism, an often fatal neuroparalytic disease, is caused by botulinum neurotoxins (BoNT) which consist of a family of seven serotypes (A-H) produced by the anaerobic bacterium Clostridium botulinum. BoNT, considered the most potent biological toxin known, is a 150 kDa protein consistin...

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Detalhes bibliográficos
Main Authors: Scotcher, Miles C., McGarvey, Jeffery A., Johnson, Eric A., Stanker, Larry H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2654115/
https://ncbi.nlm.nih.gov/pubmed/19290051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004924
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