PIM2 Induced COX-2 and MMP-9 Expression in Macrophages Requires PI3K and Notch1 Signaling

Activation of inflammatory immune responses during granuloma formation by the host upon infection of mycobacteria is one of the crucial steps that is often associated with tissue remodeling and breakdown of the extracellular matrix. In these complex processes, cyclooxygenase-2 (COX-2) plays a major...

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Autores principales: Bansal, Kushagra, Kapoor, Nisha, Narayana, Yeddula, Puzo, Germain, Gilleron, Martine, Balaji, Kithiganahalli Narayanaswamy
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2009
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2654112/
https://ncbi.nlm.nih.gov/pubmed/19290049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004911
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