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Determination of Kinetic Parameters of Enzyme-Catalyzed Reaction A + B + C → Products with the Minimum Number of Velocity Measurements

Rapid-equilibrium rate equations are derived for the five different mechanisms for the enzymatic catalysis of A + B + C → products using a computer. These rate equations are used to determine the minimum number of velocities required to estimate the values of the kinetic parameters. The rate equatio...

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Bibliografiske detaljer
Hovedforfatter: Alberty, Robert A.
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2009
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2654092/
https://ncbi.nlm.nih.gov/pubmed/19159341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp8080436
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