CFTR Functions as a Bicarbonate Channel in Pancreatic Duct Cells

Pancreatic duct epithelium secretes a HCO(3)(−)-rich fluid by a mechanism dependent on cystic fibrosis transmembrane conductance regulator (CFTR) in the apical membrane. However, the exact role of CFTR remains unclear. One possibility is that the HCO(3)(−) permeability of CFTR provides a pathway for...

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Bibliographic Details
Main Authors: Ishiguro, Hiroshi, Steward, Martin C., Naruse, Satoru, Ko, Shigeru B.H., Goto, Hidemi, Case, R. Maynard, Kondo, Takaharu, Yamamoto, Akiko
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2654087/
https://ncbi.nlm.nih.gov/pubmed/19204187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200810122
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