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Hepatocyte RXR alpha deletion in mice leads to inhibition of angiogenesis

To investigate the effect of RXRα deficiency in liver on angiogenesis, hepatocyte RXRα-deficient and control wild-type mice were fed either standard or high-fat diet (HF) for 7 weeks. In the 6th week of feeding, Matrigel model of in vivo angiogenesis was applied. Matrigel plug infiltrating cells wer...

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Bibliographic Details
Main Authors: Razny, Urszula, Wator, Lukasz, Polus, Anna, Wan, Yu-Jui Yvonne, Dyduch, Grzegorz, Tomaszewska, Romana, Dembinska-Kiec, Aldona
Format: Artigo
Language:Inglês
Published: Springer-Verlag 2009
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2654051/
https://ncbi.nlm.nih.gov/pubmed/19224264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12263-009-0111-z
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