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Decoy Methods for Assessing False Positives and False Discovery Rates in Shotgun Proteomics

The potential of getting a significant number of false positives (FPs) in peptide-spectrum matches (PSMs) obtained by proteomic database search has been well-recognized. Among the attempts to assess FPs, the concomitant use of target and decoy databases is widely practiced. By adjusting filtering cr...

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Autors principals: Wang, Guanghui, Wu, Wells W., Zhang, Zheng, Masilamani, Shyama, Shen, Rong-Fong
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2653784/
https://ncbi.nlm.nih.gov/pubmed/19061407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac801664q
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