Increased tumour dihydroceramide production after Photofrin-PDT alone and improved tumour response after the combination with the ceramide analogue LCL29. Evidence from mouse squamous cell carcinomas

Photodynamic therapy (PDT) has been proven effective for treatment of several types of cancer. Photodynamic therapy alone, however, attains limited cures with some tumours and there is need for its improved efficacy in such cases. Sphingolipid (SL) analogues can promote tumour response in combinatio...

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Detalhes bibliográficos
Main Authors: Separovic, D, Bielawski, J, Pierce, J S, Merchant, S, Tarca, A L, Ogretmen, B, Korbelik, M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Translational Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2653738/
https://ncbi.nlm.nih.gov/pubmed/19223911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604896
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