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C3a Mediates Epithelial-to-Mesenchymal Transition in Proteinuric Nephropathy

Tubulointerstitial inflammation and progressive fibrosis are common pathways that lead to kidney failure in proteinuric nephropathies. Activation of the complement system has been implicated in the development of tubulointerstitial injury in clinical and animal studies, but the mechanism by which co...

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Detalhes bibliográficos
Main Authors: Tang, Ziyong, Lu, Bao, Hatch, Ellen, Sacks, Steven H., Sheerin, Neil S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2653680/
https://ncbi.nlm.nih.gov/pubmed/19158354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2008040434
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