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Capturing the Spectrum of Interaction Effects in Genetic Association Studies by Simulated Evaporative Cooling Network Analysis

Evidence from human genetic studies of several disorders suggests that interactions between alleles at multiple genes play an important role in influencing phenotypic expression. Analytical methods for identifying Mendelian disease genes are not appropriate when applied to common multigenic diseases...

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Hlavní autoři: McKinney, Brett A., Crowe, James E., Guo, Jingyu, Tian, Dehua
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2653647/
https://ncbi.nlm.nih.gov/pubmed/19300503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000432
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