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Genistein-mediated inhibition of glycosaminoglycan synthesis, which corrects storage in cells of patients suffering from mucopolysaccharidoses, acts by influencing an epidermal growth factor-dependent pathway

BACKGROUND: Mucopolysaccharidoses (MPS) are inherited metabolic disorders caused by mutations leading to dysfunction of one of enzymes involved in degradation of glycosaminoglycans (GAGs). Due to their impaired degradation, GAGs accumulate in cells of patients, which results in dysfunction of tissue...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Jakóbkiewicz-Banecka, Joanna, Piotrowska, Ewa, Narajczyk, Magdalena, Barańska, Sylwia, Węgrzyn, Grzegorz
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: BioMed Central 2009
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2653532/
https://ncbi.nlm.nih.gov/pubmed/19272193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1423-0127-16-26
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