Production and purification of immunologically active core protein p24 from HIV-1 fused to ricin toxin B subunit in E. coli

BACKGROUND: Gag protein from HIV-1 is a polyprotein of 55 kDa, which, during viral maturation, is cleaved to release matrix p17, core p24 and nucleocapsid proteins. The p24 antigen contains epitopes that prime helper CD4 T-cells, which have been demonstrated to be protective and it can elicit lympho...

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Detalhes bibliográficos
Main Authors: Donayre-Torres, Alberto J, Esquivel-Soto, Ernesto, Gutiérrez-Xicoténcatl, María de Lourdes, Esquivel-Guadarrama, Fernando R, Gómez-Lim, Miguel A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2653483/
https://ncbi.nlm.nih.gov/pubmed/19196485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-6-17
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