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Maternal Groucho and bHLH repressors amplify the dose-sensitive X chromosome signal in Drosophila sex determination
In Drosophila, XX embryos are fated to develop as females, and XY embryos as males, because the diplo-X dose of four X-linked signal element genes, XSEs, activates the Sex-lethal establishment promoter, SxlPe, whereas the haplo-X XSE dose leaves SxlPe off. The threshold response of SxlPe to XSE conc...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2653429/ https://ncbi.nlm.nih.gov/pubmed/18773886 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2008.08.012 |
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