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Toward a chemical mechanism of proton pumping by the B-type cytochrome c oxidases: Application of Density Functional Theory to cytochrome ba(3) of Thermus thermophilus

A mechanism for proton pumping by the B-type cytochrome c oxidases is presented in which one proton is pumped in conjunction with the weakly-exergonic, two-electron reduction of Fe-bound O(2) to the Fe-Cu bridging peroxodianion, and three protons are pumped in conjunction with the highly-exergonic,...

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Bibliografiske detaljer
Main Authors: Fee, James A., Case, David A., Noodleman, Louis
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2653421/
https://ncbi.nlm.nih.gov/pubmed/18928258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja803112w
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