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Deletion of the Protein Kinase A Regulatory Subunit Leads to Deregulation of Mitochondrial Activation and Nuclear Duplication in Aspergillus fumigatus

Proper regulation of the cyclic AMP-dependent protein kinase (PKA) pathway is required for normal growth and development in many fungi. We have reported that deletion of the PKA regulatory subunit gene, pkaR, in Aspergillus fumigatus leads to defects in germination and a hypersensitivity of conidia...

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Autors principals: Fuller, Kevin K., Zhao, Wei, Askew, David S., Rhodes, Judith C.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2653251/
https://ncbi.nlm.nih.gov/pubmed/19124579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00391-08
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