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Microfludic Device for Creating Ionic Strength Gradients over DNA Microarrays for Efficient DNA Melting Studies and Assay Development

The development of DNA microarray assays is hampered by two important aspects: processing of the microarrays is done under a single stringency condition, and characteristics such as melting temperature are difficult to predict for immobilized probes. A technical solution to these limitations is to u...

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Detalhes bibliográficos
Main Authors: Petersen, Jesper, Poulsen, Lena, Birgens, Henrik, Dufva, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2653225/
https://ncbi.nlm.nih.gov/pubmed/19277213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004808
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