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Folding mechanism of reduced cytochrome c: Equilibrium and kinetic properties in the presence of carbon monoxide

Despite close structural similarity, the ferric and ferrous forms of cytochrome c (cyt c) differ greatly in terms of their ligand binding properties, stability, folding and dynamics. The reduced heme iron binds diatomic ligands such as CO only under destabilizing conditions that promote weakening or...

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Detalhes bibliográficos
Main Authors: Latypov, Ramil F., Maki, Kosuke, Cheng, Hong, Luck, Stanley D., Roder, Heinrich
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2653224/
https://ncbi.nlm.nih.gov/pubmed/18761351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.08.025
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