Lymphangiosis carcinomatosa in squamous cell carcinomas of larynx and hypopharynx – value of conventional evaluation and additional immunohistochemical staining of D2-40

BACKGROUND: Recent studies revealed a predictive value of lymphatic vessel invasion (L1) for the nodal metastasizing and poor prognosis in malignant tumors at different sites. The monoclonal antibody D2-40 (podoplanin) stains specifically endothelial cells of lymphatic vessels and improves the searc...

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Bibliographische Detailangaben
Hauptverfasser: Völker, Hans-Ullrich, Scheich, Matthias, Nowack, Isabell, Metzger, Alexandra, Haubitz, Imme, Puppe, Bernhard, Hagen, Rudolf, Müller-Hermelink, Hans-Konrad, Völter, Christiane
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2009
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2653073/
https://ncbi.nlm.nih.gov/pubmed/19261178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-7819-7-25
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