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Mouse models of oxidative phosphorylation dysfunction and disease

Oxidative phosphorylation (OXPHOS) deficiency results in a number of human diseases, affecting at least one in 5000 of the general population. Altering the function of genes by mutations are central to our understanding their function. Prior to the development of gene targeting, this approach was li...

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Autors principals: Vempati, Uma D., Torraco, Alessandra, Moraes, Carlos T.
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652743/
https://ncbi.nlm.nih.gov/pubmed/18848991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2008.09.008
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