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Effects of (+)-Methamphetamine on Path Integration and Spatial Learning, but not Locomotor Activity or Acoustic Startle, Align with the Stress Hyporesponsive Period in Rats

Rats treated with (+)-methamphetamine (MA) on postnatal (P) days 11−20 exhibit long-term spatial and path integration (Morris and Cincinnati water mazes) learning deficits whereas those treated on P1−10 do not. MA-treatment increases corticosterone release in an age-dependent U-shaped pattern that c...

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Bibliografske podrobnosti
Main Authors: Vorhees, Charles V., Skelton, Matthew R., Grace, Curtis E., Schaefer, Tori L., Graham, Devon L., Braun, Amanda A., Williams, Michael T.
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652512/
https://ncbi.nlm.nih.gov/pubmed/19136054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijdevneu.2008.12.003
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