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Diversity Synthesis of Complex Pyridines Yields a Probe of a Neurotrophic Signaling Pathway
[Image: see text] Recognizing the value of including complex pyridines in small-molecule screening collections, we developed a previously unexplored [2 + 2 + 2]-cycloaddition of silyl-tethered diynes with nitriles. The tether provides high regioselectivity, while the solvent THF allows catalytic CpC...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical Society
2008
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2652409/ https://ncbi.nlm.nih.gov/pubmed/18510333 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol8004936 |
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