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A General Quantitative Genetic Model for Haplotyping a Complex Trait in Humans

Uncertainty about linkage phases of multiple single nucleotide polymorphisms (SNPs) in heterozygous diploids challenges the identification of specific DNA sequence variants that encode a complex trait. A statistical technique implemented with the EM algorithm has been developed to infer the effects...

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Detalhes bibliográficos
Main Authors: Wu, Song, Yang, Jie, Wang, Chenguang, Wu, Rongling
Formato: Artigo
Idioma:Inglês
Publicado em: Bentham Science Publishers Ltd. 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652406/
https://ncbi.nlm.nih.gov/pubmed/19384430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/138920207782446179
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