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The Atonal Proneural Transcription Factor Links Differentiation and Tumor Formation in Drosophila

The acquisition of terminal cell fate and onset of differentiation are instructed by cell type–specific master control genes. Loss of differentiation is frequently observed during cancer progression, but the underlying causes and mechanisms remain poorly understood. We tested the hypothesis that mas...

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Détails bibliographiques
Auteurs principaux: Bossuyt, Wouter, De Geest, Natalie, Aerts, Stein, Leenaerts, Iris, Marynen, Peter, Hassan, Bassem A
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652389/
https://ncbi.nlm.nih.gov/pubmed/19243220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1000040
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