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Activation of Dual Oxidases Duox1 and Duox2: DIFFERENTIAL REGULATION MEDIATED BY cAMP-DEPENDENT PROTEIN KINASE AND PROTEIN KINASE C-DEPENDENT PHOSPHORYLATION

Dual oxidases were initially identified as NADPH oxidases producing H(2)O(2) necessary for thyroid hormone biosynthesis. The crucial role of Duox2 has been demonstrated in patients suffering from partial iodide organification defect caused by bi-allelic mutations in the DUOX2 gene. However, the Duox...

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Bibliographic Details
Main Authors: Rigutto, Sabrina, Hoste, Candice, Grasberger, Helmut, Milenkovic, Milutin, Communi, David, Dumont, Jacques E., Corvilain, Bernard, Miot, Françoise, De Deken, Xavier
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2009
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652333/
https://ncbi.nlm.nih.gov/pubmed/19144650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M806893200
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