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Loss of c/EBP-β activity promotes the adaptive to apoptotic switch in hypoxic cortical neurons
Understanding the mechanisms governing the switch between hypoxia-induced adaptive and pathological transcription may reveal novel therapeutic targets for stroke. Using an in vitro hypoxia model that temporally separates these divergent responses, we found apoptotic signaling was preceded by a decli...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2652244/ https://ncbi.nlm.nih.gov/pubmed/18439838 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcn.2008.01.014 |
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