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Loss of c/EBP-β activity promotes the adaptive to apoptotic switch in hypoxic cortical neurons

Understanding the mechanisms governing the switch between hypoxia-induced adaptive and pathological transcription may reveal novel therapeutic targets for stroke. Using an in vitro hypoxia model that temporally separates these divergent responses, we found apoptotic signaling was preceded by a decli...

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Detalhes bibliográficos
Main Authors: Halterman, Marc W., De Jesus, Christopher, Rempe, David A., Schor, Nina F., Federoff, Howard J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652244/
https://ncbi.nlm.nih.gov/pubmed/18439838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcn.2008.01.014
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